Blar i forfatter "Kanse, Sandip"

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    • Elevated complement C3 and C4 levels are associated with postnatal pregnancy-related venous thrombosis 

      Dahm, Anders Erik A; Jacobsen, Eva-Marie; Wik, Hilde Skuterud; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Kanse, Sandip; Sandset, Per Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-29)
      High levels of complement C3 are associated with venous thrombosis (VT) in the general population. We investigated if high C3 and C4 levels were associated with pregnancy-related VT. We undertook the Norwegian VIP study, a case–control study of VT in pregnancy or within 3 months postpartum (cases, n = 313) and women without pregnancy-related VT (controls, <i>n</i> = 353). Determinants of C3 and C4 ...

    • Factor VII activating protease (FSAP) is not essential in the pathophysiology of angioedema in patients with C1 inhibitor deficiency 

      Gramstad, Olav Rogde; Kandanur, Sai Priya Sarma; Etscheid, Michael; Nielsen, Erik Waage; Kanse, Sandip (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-29)
      Background: Excessive bradykinin (BK) generation from high molecular weight kininogen (HK) by plasma kallikrein (PK) due to lack of protease inhibition is central to the pathophysiology of hereditary angioedema (HAE). Inadequate protease inhibition may contribute to HAE through a number of plasma proteases including factor VII activating protease (FSAP) that can also cleave HK.<p> <p>Objective: ...